Lupus is caused by a specific defect in the immune system that can be reversed, potentially curing the autoimmune disorder, a new study claims.

The disease appears to be caused by malfunctions in an immune system pathway that regulates cells' response to environmental pollutants, bacteria and toxins.

Insufficient activation of this pathway, controlled by the aryl hydrocarbon recepto...

People with autoimmune disorders such as lupus, type 1 diabetes and rheumatoid arthritis tend to have fewer children, and women with this class of illnesses often have higher risks for complications of pregnancy, new research shows.

Researchers in Finland compared pregnancy and childbirth outcomes for the roughly 8% of Finnish adults who have some form of autoimmune disorder to people wit...

Women are much more prone than men to develop autoimmune diseases like rheumatoid arthritis, multiple sclerosis and lupus.

Now, researchers have come up with a potential explanation for that -- one that's rooted in genes that drive a person's gender.

The female body has a complex means by which it handles the additional X chromosome, and it appears this process also renders some wom...

Flare-ups of the autoimmune condition lupus may be caused by growth of a particular gut bacteria, researchers say.

This knowledge could potentially lead to new and more successful treatments to prevent these flares, they added.

These recurrent bouts of systemic lupus erythematosus, where the body's immune systems attacks its own tissues, were strongly linked with blooms of the gut ...

Pregnant women with lupus face potential complications, including a greater risk of premature birth, according to a new U.S. study.

A 10-year audit of hospital records found that these women have more than twice the risk of giving birth to a baby who is premature or growth-restricted. The audit also found that blood transfusions are nearly four times more likely for moms-to-be with lupus,...

Skin conditions may be the first sign that a person has a rheumatic disease that will also affect the joints, muscles or ligaments.

It's essential to know what to look for, said Dr. Kathryn Dao, an associate professor of internal medicine in the Division of Rheumatic Diseases at UT Southwester...

While there's no cure for lupus and treatments don't work for many of the 1.5 million people who live with the disease in the United States, a new study shows a cancer therapy may kick hard-to-treat lupus into remission.

Lupus is an autoimmune disease that occurs when the body's immune system engages in friendly f...

People with autoimmune disorders like lupus, rheumatoid arthritis or psoriasis who suffer a heart attack are more likely to die or develop severe heart-related complications in the aftermath, a new study shows.

A heart attack creates more serious health consequences in those patients than in those who aren't battling an